Clinical significance and evaluation of proteinuria in NIDDM patients

The proteinuria may reach massive proportions resulting in the nephrotic syndrome. Early and simple diagnostic may prevent further complications. Attempts are made to correlate a simple parameters like pH, specific gravity, excretion of reducing sugar and protein profile on SDS-PAGE, an advanced technique. The pH ranged between 5.7 to 9. However, specific gravity of the urine showed significant increase from 1.000 to 1.088 and has linear relation with percentage of sugar (0.2 to 2 gm) and protein banding 1 to 5 on SDS-PAGE.