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Predominant phage types of coagulase positive staphylococci in hospital infections

U Arora1, T Jesupadam, P K Jain

  • 1G.G.S. Medical College, Faridkot.

Indian Journal of Medical Sciences
|May 8, 2000
PubMed

Insights

Bacteriophage typing revealed Staphylococcus aureus phage group distribution in clinical isolates. A high prevalence of multiple drug-resistant strains was observed, highlighting significant antimicrobial resistance challenges.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Bacteriology

Background:

  • Staphylococcus aureus is a significant human pathogen.
  • Understanding its phage types and antibiotic resistance patterns is crucial for infection control.

Purpose of the Study:

  • To characterize the phage types of Staphylococcus aureus clinical isolates.
  • To determine the antibiotic resistance profiles of these isolates.

Main Methods:

  • 360 Staphylococcus aureus strains from clinical specimens were analyzed.
  • Bacteriophage typing was performed to classify strains into phage groups.
  • Antibiotic sensitivity testing was conducted for all isolates.

Main Results:

  • 68.6% of strains were typable by bacteriophage typing.
  • The mixed phage group was the most prevalent (29.72%).
  • 79.7% of strains exhibited multiple drug resistance.

Conclusions:

  • Phage typing provides insights into the epidemiology of Staphylococcus aureus.
  • The high rate of multidrug resistance in Staphylococcus aureus clinical isolates is a major concern.

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