Related Experiment Videos
[Trichosporon--experience with species identification from human isolates]
1Katedra dermatovenerológie, Slovenská postgraduálna akadémia medicíny, Bratislava.
Summary
Dominant Trichosporon species in human isolates were T. mucoides and T. asahii. Most strains showed resistance to 5-fluorocytosine and susceptibility to polyene and azole antifungals.
Area of Science:
- Medical Mycology
- Clinical Microbiology
- Fungal Taxonomy
Context:
- The study investigated the prevalence and characteristics of Trichosporon species in 162 human isolates.
- Accurate identification of Trichosporon species is crucial for understanding their role in human infections.
Purpose:
- To identify and classify dominant Trichosporon species from human isolates.
- To assess the antifungal susceptibility patterns of these Trichosporon strains.
Summary:
- Trichosporon mucoides (41%) and Trichosporon asahii (33%) were the most prevalent species identified.
- Less than 10% of isolates belonged to the previously common Trichosporon cutaneum.
- Physiological and biological variability hindered the classification of 5% of strains.
- Antifungal susceptibility testing revealed resistance to 5-fluorocytosine and sensitivity to polyene and azole antimycotics.
Impact:
- Provides insights into the current epidemiological landscape of Trichosporon infections.
- Informs clinical treatment strategies by highlighting antifungal resistance and susceptibility patterns.
- Contributes to the taxonomic understanding of Trichosporon species in clinical settings.