Related Experiment Videos
[Papular mucinosis associated with myopathy]
1Service de Dermatologie-Vénéréologie (Pr Verret), CHU 49033 Angers Cedex 01.
Annales De Dermatologie Et De Venereologie
|May 11, 2000
Summary
Papular mucinosis can be linked to myopathy, presenting as muscle weakness and difficulty swallowing. Corticosteroid therapy effectively treated skin lesions in a case study.
Area of Science:
- Dermatology
- Neurology
- Rheumatology
Background:
- Papular mucinosis is a rare skin condition.
- It can be associated with underlying myopathy.
Observation:
- A 54-year-old woman presented with widespread, itchy papules.
- Skin biopsy revealed dermal mucin deposits.
- She also experienced proximal muscle weakness and dysphagia.
Findings:
- Serum analysis showed a monoclonal lambda IgG.
- Elevated creatine phosphokinase and myogenic electromyography confirmed myopathy.
- Muscle biopsy showed polymyositis without mucin deposits.
Implications:
- Myopathy associated with papular mucinosis typically involves proximal muscle weakness and dysphagia.
- Corticosteroid therapy showed efficacy in resolving skin lesions.
- The pathophysiology remains unclear, but the association is likely not coincidental.