Related Experiment Video
Updated: Aug 7, 2026

08:08
An in vivo Rodent Model of Contraction-induced Injury and Non-invasive Monitoring of Recovery
Published on: May 11, 2011
Nerve injury associated with plantarflexion-inversion ankle sprains
D W Hayes1, V J Mandracchia, G E Webb
1Broadlawns Medical Center, Des Moines, Iowa, USA.
Clinics in Podiatric Medicine and Surgery
|May 16, 2000
Summary
Severe ankle sprains can cause uncommon nerve injuries. This article details nerve damage mechanisms, symptoms, and treatments following plantarflexion-inversion injuries.
Area of Science:
- Orthopedics
- Neurology
- Sports Medicine
Background:
- Ankle sprains are common injuries, often involving ligamentous damage.
- Severe plantarflexion-inversion ankle sprains can lead to less common nerve pathologies.
- Understanding the neuroanatomy of the lower extremity is crucial for diagnosing nerve injuries.
Purpose of the Study:
- To describe infrequently reported nerve pathologies associated with severe ankle sprains.
- To elucidate the mechanisms of nerve injury in these specific ankle trauma cases.
- To outline diagnostic presentations and therapeutic options for associated nerve injuries.
Main Methods:
- Review of anatomical structures of the lower extremity, focusing on neurologic elements.
- Analysis of biomechanical mechanisms leading to nerve damage during ankle sprains.
- Synthesis of clinical presentations and treatment strategies from existing literature.
Main Results:
- Identification of specific, less-frequently described nerve pathologies linked to severe ankle sprains.
- Explanation of how plantarflexion-inversion forces can cause nerve injury.
- Description of typical clinical signs and symptoms of these nerve injuries.
Conclusions:
- Nerve pathologies are an under-recognized complication of severe ankle sprains.
- Accurate diagnosis requires understanding lower extremity neuroanatomy and injury mechanisms.
- Prompt recognition and appropriate management can improve patient outcomes.
Related Concept Videos
Pulse Assessment Sites
Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
Ankle Joint
The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
Muscles of the Leg that Move the Foot and Toes
The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles.
Reflex Activity
A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort.
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
Somatic Spinal Reflexes
Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

