Related Experiment Video

Updated: Aug 17, 2026

Minimal Erythema Dose (MED) Testing
06:24

Minimal Erythema Dose (MED) Testing

Published on: May 28, 2013

Pediatric exanthems

E K Gable1, G Liu, D S Morrell

  • 1Pediatric Teaching Program, Moses Cone Health System, Greensboro AHEC, Greensboro, North Carolina 27401, USA.

Primary Care
|May 18, 2000
PubMed

Insights

Pediatric exanthems, or childhood rashes, are often caused by over 50 different agents. This article provides a systematic approach to diagnosing 12 common childhood exanthems by analyzing rash characteristics and symptoms.

Area of Science:

  • Pediatrics
  • Dermatology
  • Infectious Diseases

Background:

  • Childhood diseases frequently present with cutaneous manifestations, specifically exanthems.
  • Over 50 causative agents, including viral, bacterial, and rickettsial pathogens, are known to cause exanthems in children.
  • Accurate diagnosis of exanthems is crucial for appropriate management and public health.

Purpose of the Study:

  • To present a systematic diagnostic approach for evaluating common childhood exanthems.
  • To aid clinicians in differentiating between various causes of pediatric rashes.
  • To correlate clinical presentation with specific etiologies.

Main Methods:

  • Review of common pediatric exanthems and their clinical features.
  • Correlation of rash morphology, distribution, and timing with constitutional signs and symptoms.
  • Systematic evaluation framework for 12 prevalent exanthems.

Main Results:

  • Identification of key diagnostic features for common childhood exanthems.
  • Emphasis on the importance of clinical correlation for accurate diagnosis.
  • A structured approach aids in differentiating over 50 potential causative agents.

Conclusions:

  • A systematic approach, integrating rash characteristics and clinical context, is effective for diagnosing childhood exanthems.
  • Understanding the location, morphology, and timing of eruptions is vital.
  • Diagnosis relies on correlating eruption patterns with associated signs and symptoms.

Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Chickenpox01:20

Chickenpox

Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...