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Iris varix simulating an iris melanoma.

J A Shields1, C L Shields, J Pulido

  • 1Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|May 18, 2000
PubMed
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Thrombosed iris varix, a rare condition, can mimic iris melanoma. This case highlights the importance of considering iris varix in the differential diagnosis of iris masses.

Area of Science:

  • Ophthalmology
  • Vascular Malformations
  • Ophthalmic Pathology

Background:

  • Iris varix is an uncommon vascular anomaly of the iris.
  • Clinical characteristics and diagnostic challenges of iris varix are not well-established.
  • Distinguishing iris varix from malignant lesions like iris melanoma is crucial for appropriate management.

Observation:

  • A 53-year-old male presented with a dark brown iris mass and hyphema in the left eye.
  • Ultrasound biomicroscopy identified a circumscribed iris stromal mass.
  • The clinical presentation raised suspicion for iris melanoma.

Findings:

  • Surgical excision and histopathologic examination revealed a thrombosed iris varix.
  • The lesion showed stromal hemorrhage with vascular marker-positive endothelial cells.

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  • The final diagnosis confirmed a thrombosed iris varix, not melanoma.

    • Implications:

    • This case underscores that thrombosed iris varix can clinically simulate iris melanoma.
    • Iris varix should be included in the differential diagnosis for patients presenting with iris masses.
    • Accurate diagnosis is essential to avoid unnecessary aggressive treatment for benign conditions.