Related Experiment Video

Updated: Oct 16, 2026

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
09:59

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

[Use of antibiotics among Danish children in 1998. Consumption on a national basis]

H L Johansen1, J M Kampmann, B K Ingvardsen

  • 1hjo@dkma.dk

Ugeskrift for Laeger
|May 18, 2000
PubMed

Insights

Antibiotic use was high among Danish children in 1998, with 33% receiving prescriptions. Younger children, especially 1-year-olds, were more likely to receive broad-spectrum antibiotics.

Area of Science:

  • Pediatric infectious disease epidemiology
  • Antimicrobial stewardship

Context:

  • Antibiotic prescribing patterns in pediatric populations are crucial for public health.
  • Understanding age-specific antibiotic utilization informs targeted interventions.

Purpose:

  • To evaluate the patterns and trends of antibiotic (AB) use in Danish children aged 0-15 years during 1998.
  • To analyze age-related differences in antibiotic prescribing, including the use of broad-spectrum agents.

Summary:

  • A comprehensive analysis of 585,491 antibiotic prescriptions for 331,979 Danish children in 1998 revealed that 33% received at least one prescription.
  • Antibiotic use was significantly higher in younger children, with a one-year prevalence of 63.2% for 1-year-olds compared to 18.3% for 12-year-olds.
  • General practitioners issued 83% of all antibiotic prescriptions, and younger children were more frequently prescribed broad-spectrum antibiotics.

Impact:

  • Findings highlight a notable trend of increased antibiotic prescribing in younger pediatric populations, particularly broad-spectrum agents.
  • This study provides essential data for developing targeted antimicrobial stewardship programs to optimize antibiotic use in children.
  • Results underscore the need for continued surveillance of antibiotic prescribing practices in pediatric populations to combat antimicrobial resistance.

More Related Videos

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Related Concept Videos

Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...
Antibiotic Selection01:45

Antibiotic Selection

Researchers use antibiotic resistance genes to identify bacteria that possess a plasmid containing their gene of interest. Antibiotic resistance naturally occurs when a spontaneous DNA mutation creates changes in bacterial genes that eliminate antibiotic activity. Bacteria can share these new resistance genes with their offspring and other bacteria. The overuse and misuse of antibiotics have created a public health crisis, as resistant and multi-resistant bacteria continue to develop.Antibiotic...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...