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Analyzing and Building Nucleic Acid Structures with 3DNA
Published on: April 26, 2013
Spatial distribution functions as a tool in the analysis of ribonucleic acids hydration--molecular dynamics studies
K Kulińska1, T Kuliński, A Lyubartsev
1Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań. kasiak@ibch.poznan.pl
Computers & Chemistry
|May 18, 2000
Abstract:
The spatial distribution functions (SDFs) determined as three-dimensional density distribution of hydrogen and oxygen atoms of water in a local coordinate system linked with RNA molecule are used to study details of the spatial structure of aqueous solution around selected parts of RNA duplexes: r(CGCGCG)2 and 2'-O-Me(CGCGCG)2. The influence of the 2'-O-methylation on the hydration pattern of RNA helical fragments is visualized at the atomic level.

