[Combination of hormone replacement therapy with buspirone in the treatment of climacteric complaints]

At the menopause outpatient unit among 100 patients with climacteric problems 50 were treated with continuous hormone replacement therapy alone (Group A), and in 50 other cases were given a combination of a half dose hormone replacement therapy (HRT) and anxiolytic drug (Group B). After a 3 month treatment period the complaints were reduced at the same extent in both groups. The frequency of the side effects was similar in both groups. The combination of a reduced dose of HRT and an anxiolytic drug can be an alternative treatment to patients refusing HRT because of cancerophobia or side effects and to those, whom the reduced dose of HRT might be sufficient to avoid climacteric complaints.