[Efficacy of combined oral hormone replacement therapy in postmenopausal symptoms]

The authors analyzed their observations with a fix combination of estrogen and progestogen pill-Kliogest. The protocol and treatment used in this study are reported. Treatment was the most effective in early postmenopausal complaints (flush), but was effective to prevent insomnia, neurotic complaints and urinary problems. The treatment was the less effective to treat pains in connection with osteoporosis. Endometrial atrophy was found by vaginal ultrasonography on the one year follow-up visit. There was no change in the labor parameters on the one year follow up visit. The most common side effects were metrorrhagia and breast tension. In the authors opinion combined per os hormonal replacement therapy treatment is an effective, simple and well tolerated method to treat some of the postmenopausal complaints.