Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Left atrial appendage function in patients with different pacing modes.

F Ertaş1, S Güleç, I Dinçer

  • 1Department of Cardiology, Medical School of Ankara University, Ankara, Turkey. ertasf@hotmail.com

International Journal of Cardiology
|May 19, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of HLA B27 in Patients Diagnosed with Ankylosing Spondylitis (AS) in Diyarbakır, Southeastern Region of Turkey.

Nigerian journal of clinical practice·2024
Same author

Global longitudinal strain score predicts all cause death in patients with chronic total occlusion with preserved ejection fraction.

European review for medical and pharmacological sciences·2022
Same author

Development and performance assessment of new solar and fuel cell-powered oxygen generators and ventilators for COVID-19 patients.

International journal of hydrogen energy·2021
Same author

Development and analysis of a new renewable energy-based industrial wastewater treatment system.

Journal of environmental management·2021
Same author

Development and multi-objective optimization of a newly proposed industrial heat recovery based cascaded hydrogen and ammonia synthesis system.

The Science of the total environment·2020
Same author

Defying gravity: Drops that climb up a vertical wall of their own accord.

Journal of colloid and interface science·2019
Same journal

Clinical outcomes of intravascular imaging-guided versus angiography-guided drug-coated balloon angioplasty for de novo coronary lesions.

International journal of cardiology·2026
Same journal

Hypertension management in obstructive hypertrophic cardiomyopathy patients treated with cardiac myosin inhibitors - real world data.

International journal of cardiology·2026
Same journal

Fully quantitative CMR rest perfusion reveals myocardial perfusion abnormality in Kawasaki disease: Association with left ventricular Remodeling.

International journal of cardiology·2026
Same journal

Predicted adherence and ischaemic stroke risk in atrial fibrillation patients initiating oral anticoagulation: A cohort study of the medication adherence score.

International journal of cardiology·2026
Same journal

Severe tricuspid regurgitation is a congestion-driven cardiorenal disease: A longitudinal study defining a right heart failure phenotype.

International journal of cardiology·2026
Same journal

Applicability of ischemic heart disease clinical practice guidelines in low- and middle-income countries.

International journal of cardiology·2026
See all related articles

Ventricular pacing significantly impairs left atrial appendage function compared to physiological pacing, increasing thromboembolism risk, especially in sick sinus syndrome patients.

Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • Ventricular pacemakers are linked to higher systemic thromboembolism rates than physiological pacemakers.
  • The precise mechanisms underlying pacemaker-associated thromboembolism remain incompletely understood.

Purpose of the Study:

  • To investigate the impact of different pacemaker pacing modes on left atrial appendage (LAA) function.
  • To explore the relationship between pacing modality and LAA function in patients without atrial fibrillation, left ventricular dysfunction, or mitral valve disease.

Main Methods:

  • Multiplane transesophageal echocardiography (TEE) was used to assess LAA ejection fraction (EF), peak emptying (V(E)), and filling (V(F)) flow velocities.
  • 31 patients with pacemakers (19 with complete atrioventricular block, 12 with sick sinus syndrome) were studied, excluding those with specific cardiac conditions.

Related Experiment Videos

Main Results:

  • Patients with ventricular pacing (VVI) showed significantly lower LAA EF, V(E), and V(F) compared to those with physiological pacing (VDD or DDD).
  • This reduction in LAA function was observed in both atrioventricular block and sick sinus syndrome subgroups, with a more pronounced decrease in sick sinus syndrome patients.
  • A case of LAA thrombus was detected in a patient with sick sinus syndrome paced with VVI.

Conclusions:

  • Pacing modality significantly influences LAA function in pacemaker recipients.
  • Asynchronous ventricular pacing is associated with depressed LAA function, potentially increasing the risk of thrombus formation and thromboembolic events, particularly in patients with sick sinus syndrome.