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Updated: Aug 15, 2026

An Ex vivo Model to Study Hormone Action in the Human Breast
Published on: January 8, 2015
Hormone replacement therapy and breast cancer risk
1VA General Hospital, Athens, Greece.
Abstract:
The female breast is subject to a lifetime of hormonal control. After menopause, breast tissue becomes quiescent when estrogens drop to low levels. Menopause-associated hormonal decreases produce short- and long-term consequences that can be treated successfully by hormone replacement therapy (HRT). Despite the beneficial effects of HRT, the potential risk of breast cancer is a concern of both women and physicians. The available data indicate that HRT administered for longer than 5 years moderately increases the risk of breast cancer, but overall the benefits outweight the potential risk.
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