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Updated: Jul 20, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
10:13

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

Published on: June 9, 2017

Molecular identification and characterization of G protein-coupled receptors for lysophosphatidic acid and

S An1

  • 1Department of Medicine, University of California, San Francisco 94143-0711, USA. songzhu@itsa.ucsf.edu

Annals of the New York Academy of Sciences
|May 20, 2000
PubMed

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G-protein Coupled Receptors

G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
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