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[Scintigraphy with erythrocytes labelled in vitro with 99mTc compared with 111In-octreotide in the detection of
R García Fernández1, L Iwasaki-Otake, F Gómez-Acosta
1Departamento de Medicina Nuclear, Hospital de Oncología (HO), Centro Médico Nacional Siglo XXI (CMN), Instituto Mexicano del Seguro Social (IMSS), México, D.F.
Objective:
Demonstrate the utility of centelleography using 111In-octreotide in carotid glomus simple o multiple in comparison to erythrocytes with 99mTc calculate the sensitivity, specificity and accuracy of both test.
Design:
Comparative survey (Diagnostic test) Place: Hospital Oncológico de Concentración del Distrito Federal (Mexico).
Subjects:
Twenty patients sent to nuclear medicine service for carotid glomus diagnosis.
Main Measures:
All of the patients went under a centelleography with 111In-octreotide labeled erythrocytes. Diagnostic was confirmed with US and CAT, taking as the gold standard the selective angiography and/or histopathology.
Results:
Using 99mTc-labeled erythrocytes resulted in; True positives 13, true negatives 3, false positive 3, false negative 1. Sensitivity 92%, specificity 50%, accuracy 80% and Using 111In-octreotide: True positive 14, true negative 6, and 100% sensitivity, specificity was obtained.
Conclusions:
We consider that Centelleography with 111In-octreotide must be the selected image methodology to accurately diagnose carotid glomus, previous to surgery, or in case of patients prior to radiotherapy that because of age, damage size or location can not be candidates for surgery.
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