Jove
Visualize
Contact Us

Related Experiment Videos

Onchocerciasis presenting with lower extremity, hypopigmented macules.

W Vernick1, S E Turner, E Burov

  • 1Jefferson Medical College, Philadelphia, Pennsylvania, USA.

Cutis
|May 29, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient photo-thermal activation of gold nanoparticle-doped polymer plasmonic switches.

Optics express·2012
Same author

Importance of residual stresses in the Brillouin gain spectrum of single mode optical fibers.

Optics express·2012
Same author

Evidence of two erbium sites in standard aluminosilicate glass for EDFA.

Optics express·2010
Same author

Search for the KL-->pi 0 pi 0 e+e- decay in the KTeV experiment.

Physical review letters·2002
Same author

Radiative decay width measurements of neutral kaon excitations using the primakoff effect.

Physical review letters·2002
Same author

Coding geographic areas across census years: creating consistent definitions of metropolitan areas.

Working paper series (National Bureau of Economic Research)·2002
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Onchocerciasis, a parasitic infection, can cause skin issues like hypopigmented macules. Early diagnosis and ivermectin treatment are crucial for managing this river blindness.

Area of Science:

  • Medical Parasitology
  • Dermatology
  • Infectious Diseases

Background:

  • Onchocerciasis, or river blindness, is a significant global health concern caused by Onchocerca volvulus.
  • It is a leading cause of preventable blindness in endemic regions, affecting millions worldwide.
  • The disease manifests as a chronic, multisystem illness with ocular, cutaneous, and nodular presentations.

Observation:

  • A case study of an 18-year-old African female presenting with asymptomatic hypopigmented macules on her anterior tibiae over five years.
  • Histopathology confirmed a perivascular inflammatory infiltrate with eosinophils and microfilariae in the papillary dermis.
  • This presentation expands the differential diagnosis for hypopigmented macules, particularly in African populations.

Findings:

Related Experiment Videos

  • The patient was diagnosed with onchocerciasis based on clinical presentation and pathological findings.
  • Ivermectin, the standard treatment, was initiated for the patient.
  • The case highlights the importance of considering onchocerciasis in patients with specific dermatological manifestations.

    • Implications:

    • This case underscores the need to include onchocerciasis in the differential diagnosis of hypopigmented macules, especially in individuals from or who have resided in endemic areas.
    • Effective diagnosis and treatment strategies are vital for managing onchocerciasis in both endemic and non-endemic settings.
    • Understanding the diverse clinical presentations of onchocerciasis is crucial for timely intervention and preventing severe outcomes like blindness.