Related Experiment Video
Updated: Aug 6, 2026

05:05
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Pembrolizumab-Induced Bullous Pemphigoid: Navigating Diagnostic Challenges and Treatment Resistance
Camille Moeckel1, Sara Ferguson1
1Department of Dermatology, Penn State College of Medicine, Hershey, Pennsylvania.
Cutis
|July 24, 2026
Summary
Immune checkpoint inhibitors like pembrolizumab can cause drug-induced bullous pemphigoid in urothelial carcinoma patients. Early diagnosis and steroid-sparing agents like rituximab are crucial for managing this adverse event.
Area of Science:
- Oncology
- Dermatology
- Immunology
Background:
- Immune checkpoint inhibitors (ICIs) have transformed urothelial carcinoma treatment.
- Cutaneous immune-related adverse events are common with ICIs.
- Drug-induced bullous pemphigoid (DIBP) is a rare but serious side effect.
