Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Promoting good research practice.

G D Murray1

  • 1Department of Community Health Sciences, University of Edinburgh Medical School, UK. gordon.murray@ed.ac.uk

Statistical Methods in Medical Research
|May 29, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An international, open-label, randomised trial comparing a two-step approach versus the standard three-step approach of the WHO analgesic ladder in patients with cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2022
Same author

Elevated Baseline C-Reactive Protein as a Predictor of Outcome After Aneurysmal Subarachnoid Hemorrhage: Data From the Simvastatin in Aneurysmal Subarachnoid Hemorrhage (STASH) Trial.

Neurosurgery·2015
Same author

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events.

European journal of preventive cardiology·2013
Same author

Group therapy for people with bulimia nervosa: systematic review and meta-analysis.

Psychological medicine·2013
Same author

Systematic review of head cooling in adults after traumatic brain injury and stroke.

Health technology assessment (Winchester, England)·2012
Same author

Application of Variable Life Adjusted Display (VLAD) to risk-adjusted mortality of esophagogastric cancer surgery.

World journal of surgery·2011
Same journal

A joint model for a longitudinal outcome and a progressive multistate model under a mixed observation scheme.

Statistical methods in medical research·2026
Same journal

Efficient semi-supervised estimation of optimal individualized treatment regimes with survival outcome.

Statistical methods in medical research·2026
Same journal

Asymptotic online FWER control for dependent test statistics.

Statistical methods in medical research·2026
Same journal

Regression analysis of misclassified current status data with potentially unknown test accuracy.

Statistical methods in medical research·2026
Same journal

Bayesian multivariate linear mixed-effects models with varied association structures.

Statistical methods in medical research·2026
Same journal

Inference about the ratio of age-standardized rates between two overlapping populations.

Statistical methods in medical research·2026
See all related articles

Medical statistics has advanced significantly, but a gap exists between best practices and published research. Bridging this gap through improved study design and analysis is the profession

Area of Science:

  • Medical Statistics
  • Biostatistics
  • Health Research Methodology

Background:

  • The field of medical statistics has seen rapid methodological and technological advancements.
  • The evidence-based medicine movement has increased the recognition of biostatistics' importance.
  • A significant discrepancy exists between recognized statistical best practices and their application in published medical literature.

Purpose of the Study:

  • To highlight the advancements and challenges in medical statistics at the turn of the millennium.
  • To identify critical issues in the publication of medical research concerning statistical practices.
  • To emphasize the need to bridge the gap between statistical theory and practice in medical publications.

Main Methods:

  • Review of current practices in medical statistics and publishing.

Related Experiment Videos

  • Analysis of common statistical errors in medical literature.
  • Discussion of the implications of poor statistical reporting.

    • Main Results:

    • Methodological and computational advancements have expanded statistical capabilities.
    • Despite advancements, poor study design, inappropriate analysis, and selective reporting are prevalent in medical publications.
    • There is a notable disparity between ideal statistical methodology and its real-world application in research.

    Conclusions:

    • The most significant challenge for medical statisticians is to reconcile the gap between sound statistical practice and published research.
    • Addressing issues like poor study design and analysis is crucial for improving the quality of medical literature.
    • Efforts are needed to ensure that published medical research accurately reflects robust statistical principles.