Related Experiment Video
Updated: Aug 15, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
[Complex compounds of heparin in obstetric hemorrhages]
Abstract:
The so-called uncontrollable hemorrhage in obstetric patients correlated mainly with appearance in blood of complex heparin compounds, primarily fibrinogen-heparin, adrenaline-heparin, noradrenaline-heparin and, less frequently, plasminogen-heparin. The heparin complexes were observed in circulation when the anticoagulation system was stimulated due to appearance of thrombin in the blood stream. The complexes possessed and anticoagulation and antipolymerization effects on fibrin-monomer and caused nonenzymatic lysis of unstabilized fibrin clots.
Related Concept Videos
Coagulation
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Introduction to Hemostasis
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Coagulation
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
Extrinsic and Intrinsic Pathways of Hemostasis
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
Venous Thrombosis III: Interprofessional Care

