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Related Experiment Videos

[Eosinophilic enteritis].

P Gjersøe1, S N Rasmussen, B F Hansen

  • 1H:S Hvidovre Hospital, gastroenheden, medicinsk sektor.

Ugeskrift for Laeger
|May 29, 2000
PubMed
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Eosinophilic enteritis, a rare condition, mimicked Crohn's disease in a male patient presenting with ileal obstruction. Surgical resection and subsequent medical treatment led to remission, highlighting effective management strategies for this inflammatory bowel condition.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Eosinophilic enteritis is a rare gastrointestinal disorder characterized by eosinophilic infiltration of the bowel wall.
  • It can present with symptoms mimicking other inflammatory bowel diseases, such as Crohn's disease, leading to diagnostic challenges.

Observation:

  • A 45-year-old male presented with clinical and radiological evidence of stenotic inflammatory ileal disease, initially suspected to be Crohn's disease.
  • The patient developed a small bowel obstruction requiring surgical resection of 60 cm of the ileum.

Findings:

  • Histopathological examination of the resected ileum confirmed eosinophilic enteritis, with eosinophilic infiltration predominantly in the tunica muscularis.
  • One year post-surgery, the patient experienced a relapse with a narrowed and irregular ileum, confirmed by small bowel X-ray.

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Implications:

  • This case underscores the importance of considering eosinophilic enteritis in the differential diagnosis of stenotic inflammatory ileal disease.
  • Successful management with a combination of mesalamine, azathioprine, and cromoglicate achieved remission, suggesting a multi-faceted therapeutic approach is effective.
  • The patient remained well one and a half years post-treatment, indicating the potential for long-term remission with appropriate medical intervention.