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Related Experiment Videos

Rosai-Dorman disease causing cervical myelopathy.

J P Hollowell1, C E Wolfla, N C Shah

  • 1Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

Spine
|June 1, 2000
PubMed
Summary

Rosai-Dorman disease, a rare benign lymphoproliferative condition, can affect the spine. Early recognition of its features may lead to timely diagnosis and treatment, potentially avoiding surgery.

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Area of Science:

  • Neurology
  • Pathology
  • Oncology

Background:

  • Rosai-Dorman disease is an idiopathic benign lymphoproliferative disorder typically presenting in younger individuals with cervical lymphadenopathy.
  • Extranodal involvement is common, but spinal canal manifestation without lymphadenopathy is rare.

Observation:

  • A case report detailing an elderly male patient with Rosai-Dorman disease presenting with spinal canal mass lesions and myelopathy.
  • Clinical presentation, radiographic imaging, and pathological findings were analyzed and compared with existing literature.

Findings:

  • The patient underwent surgical decompression with incomplete lesion resection, which aided in diagnosis and treatment planning.
  • Significant neurological improvement in myelopathy symptoms was observed post-operatively.

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Implications:

  • This case highlights the importance of considering Rosai-Dorman disease in elderly patients with spinal lesions and neurological deficits.
  • Awareness of the diverse clinical presentations can facilitate earlier diagnosis and potentially guide conservative management strategies, minimizing surgical intervention.