Evidence for mild blue-yellow colour vision deficits immediately following fluorescein angiography
M J Sankeralli1, J C Chen, A B Metha
1McGill Vision Research, Department of Ophthalmology, McGill University, Montreal, Quebec, Canada.
Aims:
We have investigated the short term effects of fluorescein angiography on the blue-yellow, red-green, and luminance contrast sensitivity of patients with early age-related macular degeneration (ARMD).
Methods:
Nine ARMD patients with no exudative complications and a visual acuity of 20/60 or better in the tested eye were selected. Cardinal colour directions for the isolation of the red-green, blue-yellow and achromatic (luminance) visual mechanisms were determined for each patient. Contrast sensitivity was measured in each cardinal colour direction immediately before and 20 min after standard 20-flash fluorescein angiography.
Results:
A significant, albeit mild, reduction for blue-yellow contrast sensitivity following angiography was observed (ANOVA, alpha = 0.05). Fluorescein angiographic exposure had no significant effect on red-green or luminance contrast sensitivity.
Conclusion:
Our results show that fluorescein angiography causes at least a short term deficit selective to blue-yellow contrast sensitivity in our patient group.
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