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Infective endocarditis in infants and children.

A W Bhat1, S Jalal, V John

  • 1Department of Cardiology, Shere-I-Kashmir Institute of Medical Sciences, Srinagar, India.

Indian Journal of Pediatrics
|March 1, 1996
PubMed
Summary
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This study analyzed 28 pediatric infective endocarditis cases, finding congenital heart disease common and a 25% mortality rate. Younger children and staphylococcal infections indicated poorer prognosis in pediatric infective endocarditis.

Area of Science:

  • Pediatrics
  • Cardiology
  • Infectious Diseases

Background:

  • Infective endocarditis (IE) characteristics have evolved over recent decades.
  • Pediatric IE presents unique challenges in diagnosis and management.
  • Understanding trends in pediatric IE is crucial for improving outcomes.

Purpose of the Study:

  • To retrospectively analyze cases of infective endocarditis in children under 15 years.
  • To identify epidemiological features, causative organisms, and prognostic factors in pediatric IE.
  • To evaluate treatment outcomes and mortality rates in this cohort.

Main Methods:

  • Retrospective analysis of 28 pediatric patients with infective endocarditis.
  • Data collected from Sher-i-Kashmir Institute of Medical Sciences between December 1983 and November 1993.

Related Experiment Videos

  • Comparison of clinical characteristics, microbiology, echocardiography, and outcomes between age groups.
  • Main Results:

    • Incidence of 1.5 cases/1000 admitted children; M:F ratio of 2:1.
    • Congenital heart disease present in 85.71% of patients.
    • Streptococcus viridans and Staphylococcus aureus were common pathogens; overall mortality rate was 25%.

    Conclusions:

    • Age less than 2 years, staphylococcal infection, and negative blood cultures were associated with poor prognosis.
    • Resistant heart failure was a leading cause of death in pediatric infective endocarditis.
    • Early diagnosis and appropriate management are vital for improving survival rates.