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Infective endocarditis in infants and children
1Department of Cardiology, Shere-I-Kashmir Institute of Medical Sciences, Srinagar, India.
Indian Journal of Pediatrics
|March 1, 1996
Summary
This study analyzed 28 pediatric infective endocarditis cases, finding congenital heart disease common and a 25% mortality rate. Younger children and staphylococcal infections indicated poorer prognosis in pediatric infective endocarditis.
Area of Science:
- Pediatrics
- Cardiology
- Infectious Diseases
Background:
- Infective endocarditis (IE) characteristics have evolved over recent decades.
- Pediatric IE presents unique challenges in diagnosis and management.
- Understanding trends in pediatric IE is crucial for improving outcomes.
Purpose of the Study:
- To retrospectively analyze cases of infective endocarditis in children under 15 years.
- To identify epidemiological features, causative organisms, and prognostic factors in pediatric IE.
- To evaluate treatment outcomes and mortality rates in this cohort.
Main Methods:
- Retrospective analysis of 28 pediatric patients with infective endocarditis.
- Data collected from Sher-i-Kashmir Institute of Medical Sciences between December 1983 and November 1993.
- Comparison of clinical characteristics, microbiology, echocardiography, and outcomes between age groups.
Main Results:
- Incidence of 1.5 cases/1000 admitted children; M:F ratio of 2:1.
- Congenital heart disease present in 85.71% of patients.
- Streptococcus viridans and Staphylococcus aureus were common pathogens; overall mortality rate was 25%.
Conclusions:
- Age less than 2 years, staphylococcal infection, and negative blood cultures were associated with poor prognosis.
- Resistant heart failure was a leading cause of death in pediatric infective endocarditis.
- Early diagnosis and appropriate management are vital for improving survival rates.