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Updated: Aug 12, 2026

Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes
Published on: June 16, 2011
[Cytotoxic effect of antihuman thymocyte serum on T lymphocytes]
Abstract:
The rabbit human thymocyte serum had a selective cytotoxicity on human T lymphocytes. In the presence of guinea pig complement, 23.8% of the otal blood leukocytes were killed by the heterologus antiserum and only 4.2 % were killed by normal rabbit serum. On average 28.2% of the leukocyte preparation obtained by dextran sedmentation were lymphocytes. According to the above figures, 72.3% of the circulating lymphocytes were identified as T cells. The data were comparable to those obtained from other conventional methods used in laboratory animals. The cytotoxicity test was found to be a reliable technique for identifying human T lymphocytes.
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