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Gram-scale synthesis of (+)-discodermolide
A B Smith1, M D Kaufman, T J Beauchamp
1Department of Chemistry, Monell Chemical Senses Center, University of Pennsylvania 19104, USA. smithab@sas.upenn.edu
Abstract:
[formula: see text] A triply convergent, highly efficient second-generation synthesis of the potent antimitotic agent (+)-discodermolide (1) has been achieved on a 1-g scale.
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