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Updated: Sep 16, 2026

Assays for the Identification of Novel Antivirals against Bluetongue Virus
Published on: October 12, 2013
Soluble-polymer supported synthesis of a prostanoid library: identification of antiviral activity
1Department of Chemistry, Scripps Research Institute, La Jolla, California 92037, USA.
Abstract:
[formula: see text] The prostaglandins are potent natural products taking part in many biological processes. The "convergent generation of diversity" from a "toolbox" of prostanoid components, augmented with additional polymer-supported transformations, can enable construction of valuable libraries. A parallel-pool strategy was used to assemble a small library of prostanoids. The inhibition of a herpes-family virus demonstrated the potential for new drug discovery.
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