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Updated: Aug 16, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep-disordered breathing in children
1Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland, USA. cmarcus@welch.jhu.edu
Insights
Childhood sleep-disordered breathing, including obstructive sleep apnea, is common but often missed. Early diagnosis and treatment of these sleep-related breathing disorders can prevent serious health issues like neurocognitive deficits.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Child Health
Background:
- Sleep-disordered breathing (SDB) is prevalent in children.
- Obstructive sleep apnea syndrome is a common form of SDB.
- Complications include neurocognitive deficits, growth failure, and pulmonary hypertension.
Purpose of the Study:
- To highlight the significance of SDB in children.
- To discuss the diagnostic challenges and new syndromes like upper airway resistance syndrome.
- To emphasize the importance of polysomnography in evaluating SDB.
Main Methods:
- Review of current literature on pediatric sleep-disordered breathing.
- Discussion of diagnostic tools, particularly polysomnography.
- Description of emerging sleep-related respiratory syndromes.
Main Results:
- SDB, including obstructive sleep apnea, is frequently undiagnosed in children.
- Upper airway resistance syndrome is a newly described condition.
- Polysomnography is crucial for accurate diagnosis.
Conclusions:
- Despite being common, SDB in children is often unrecognized.
- Advances in diagnosis and management can significantly reduce associated morbidity.
- Timely intervention is key to improving outcomes for children with SDB.
Abstract:
Sleep-disordered breathing, particularly the obstructive sleep apnea syndrome, is common during childhood. Complications include neurocognitive deficits, growth failure, and pulmonary hypertension. Nevertheless, sleep-disordered breathing is often unrecognized in children. New syndromes, such as the upper airway resistance syndrome, have recently been described. Polysomnography is invaluable for the evaluation of sleep-disordered breathing. Advances in diagnosis and management can alleviate much of the morbidity previously associated with sleep-related respiratory disorders.
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