Effect of lidocaine vs ketorolac tromethamine on postoperative laparoscopy pain control: a randomized study

Objective: To evaluate and compare the effectiveness of intraperitoneal lidocaine and intramuscular ketorolac tromethamine for immediate and delayed postoperative pain management in patients undergoing laparoscopy.Methods: Design-Seventy-four patients were prospectively randomized into four groups: intraperitoneal lidocaine; intramuscular ketorolac; both drugs; neither drug.Setting-Community Teaching Hospital Outpatient Surgery Center.Patients-Private and clinic patients needing operative laparoscopy.Intervention-One hundred milligrams of lidocaine was instilled into the peritoneal cavity just before the laparoscopy was completed. Sixty milligrams of ketorolac tromethamine was administered intramuscularly approximately 30 minutes before laparoscopy was completed.Main Outcome Measurements-The amount of analgesic used, the time required in postanesthesia recovery area, and a pain intensity score were used to evaluate the postoperative pain.Results: Pain intensity scores reported by those women receiving ketorolac and both medications were less than scores of untreated controls. Groups receiving either ketorolac, lidocaine, or both drugs required less morphine postoperatively.Conclusion: Both intraperitoneal lidocaine or intramuscular ketorolac are effective in reducing the perception of pain and the amount of morphine required postoperatively.