Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

F-18 FDG Accumulation in an Octreotide Negative Merkel Cell Tumor.

Wong1, Pham, Dworkin

  • 1Department of Nuclear Medicine, William Beaumont Hospital, Royal Oak, MI, USA

Clinical Positron Imaging : Official Journal of the Institute for Clinical P.E.T
|June 6, 2000
PubMed
Summary

Positron emission tomography (PET) imaging using F-18 Fluorodeoxyglucose (FDG) effectively visualized a rare neuroendocrine Merkel cell tumor. This imaging approach helped define the tumor

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Elastic ribbon-like piezoelectric energy harvester for wearable devices with stretchable surfaces.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2017
Same author

27. PET Image Interpretation. Attenuation-Corrected (ATN) Vs Non-Attenuation Corrected (NATN) Images.

Clinical positron imaging : official journal of the Institute for Clinical P.E.T·2001
Same author

Progressive supranuclear palsy.

Clinical eye and vision care·2001
Same author

Conformity assessment

The Journal of the Acoustical Society of America·2000
Same author

Bioequivalence of a newly developed 17 beta-estradiol tablet versus an identical reference formulation

Arzneimittel-Forschung·2000
Same author

Multiple-sequence information provides protection against mis-specified potential energy functions in the lattice model of proteins

Physical review letters·2000

Area of Science:

  • Oncology
  • Nuclear Medicine
  • Radiology

Background:

  • Merkel cell tumor is a rare, aggressive neuroendocrine skin cancer.
  • Somatostatin receptor imaging is often used but can be negative in Merkel cell tumors.
  • Accurate staging is crucial for effective treatment planning.

Purpose of the Study:

  • To evaluate the utility of F-18 Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) imaging for Merkel cell tumor.
  • To assess FDG uptake in a somatostatin-receptor negative Merkel cell tumor.
  • To determine if FDG PET can delineate the extent of disease.

Main Methods:

  • Regional PET imaging with F-18 FDG was performed.
  • Whole-body Indium-111 octreotide scan was conducted prior to PET.

Related Experiment Videos

  • Pathologically proven Merkel cell tumor in the right knee region was studied.

    • Main Results:

    • The Indium-111 octreotide scan was negative.
    • F-18 FDG PET demonstrated focal abnormal uptake along the right lower extremity.
    • No evidence of distant metastasis was detected on FDG PET.
    • The PET images helped define the local extent of the tumor.

    Conclusions:

    • F-18 FDG PET imaging can visualize somatostatin-receptor negative Merkel cell tumors.
    • FDG uptake in Merkel cells suggests its potential as an imaging tool.
    • FDG PET may aid in defining the extent of this rare neuroendocrine tumor for treatment planning.