[Lymphoid tissue and the body's non-specific resistance]

In experiments on rats and mice the author and his pupils showed that nonspecific effect of stimulators brought about in the first hours following the exposure migration of cells from the lymphoid organs, increase in the number of lymphoid cells in the bone marrow by 40-60%, appearance in the bone marrow of T-cells, and increase in the number of hemopoietic cells (CFU). This contributed to the activation of hemopoiesis and to development of transient hyperplasia of the bone marrow to the stage of elevated resistance of the organism. It was shown that transplantation of T-cells performed in the first hours after the sublethal irradiation hastened regeneration of hemopoiesis. All the data indicated above testify to the role of the lymphoid tissue in nonspecific resistance of the organism.