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Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38
Y Wang1, G J Habgood, W J Christ
1Eisai Research Institute, Andover, MA 01810, USA.
Bioorganic & Medicinal Chemistry Letters
|June 8, 2000
Abstract:
Structurally simplified analogues of halichondrin B were prepared by total synthesis and found to retain potent cell growth inhibitory activity in vitro.
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