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Published on: May 19, 2020
Keratoconus and mitral valve prolapse
1Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel. lichterh@netvision.net.il
Purpose:
To investigate the prevalence of keratoconus in patients with mitral valve prolapse (MVP).
Methods:
Videokeratography was performed in 36 patients (72 eyes) with an echocardiographic diagnosis of MVP, and were compared with 25 controls. All participants underwent slit-lamp examination and completed a medical questionnaire about joint hypermobility, arthralgia, asthma, and allergic reactions.
Results:
Keratoconus was found in eight eyes (11. 1%) (P =.056) of eight patients (22.2%) (P =.049) in the MVP group and in one eye (2%) of one patient (4%) in the control group. The keratoconus was unilateral and asymptomatic in all cases. Conjunctival papillae were statistical significant higher in the MVP group (P =.015). A statistically significant intergroup difference existed in the presence of an allergic reaction (P =.001), but not in arthralgia, hypermobility of joints, or asthma.
Conclusion:
A borderline important association of MVP with keratoconus and with allergy exists. Patients with mitral valve prolapse complaining of poor vision should be suspected of having keratoconus.
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