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Related Experiment Videos

[Human orf and erythema multiforme].

I Mourtada1, M Le Tourneur, J Chevrant-Breton

  • 1Service de Dermatologie, CHU Pontchaillou, rue Henri-Le Guilloux, 35033 Rennes, France.

Annales De Dermatologie Et De Venereologie
|June 14, 2000
PubMed
Summary
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Orf virus infection, typically mild in humans, can rarely cause erythema multiforme. This case highlights a young girl

Area of Science:

  • Veterinary Dermatology
  • Human Infectious Diseases
  • Virology

Background:

  • Orf is a zoonotic disease caused by a parapoxvirus, primarily affecting sheep.
  • Human transmission is possible, usually resulting in a benign, self-limiting skin condition.
  • Rare complications of Orf infection in humans have been documented.

Observation:

  • A 13-year-old girl presented with erythema multiforme.
  • A painless, erythematous nodule on her index finger appeared 15 days post-contact with a lamb.
  • The clinical presentation and history were consistent with Orf complicated by erythema multiforme.

Findings:

  • Orf typically manifests as pustular dermatitis in sheep and a localized lesion at the inoculation site in humans.
  • While generally uncomplicated, secondary infections can occur.

Related Experiment Videos

  • Erythema multiforme is a rare but recorded complication of Orf virus infection, with 21 cases documented.

    • Implications:

    • Diagnosis of Orf relies on a history of animal contact and characteristic lesion appearance.
    • Electron microscopy can aid in diagnosis.
    • Lesions typically resolve within 4-5 weeks without specific treatment, though symptomatic therapy may be used.