Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Antibiotic prophylaxis in surgery].

J Simo1, P Matis, S Durdík

  • 1I. chirurgická klinika Fakultnej nemocnice, Mickiewiczova 13, 813 69 Bratislava 1.

Bratislavske Lekarske Listy
|June 10, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retroperitoneal abscess after urgent resection of the stomach in a geriatric patient treated with a surgical extraperitoneal approach - case report.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2023
Same author

The role of intraoperative frozen section of central neck lymph nodes in the management of patients preoperatively diagnosed with low- risk differentiated cancer.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2022
Same author

Gallbladder carcinoma - when to use laparoscopic approach?

Bratislavske lekarske listy·2021
Same author

Postoperative pancreatic fistula after pancreatic resection.

Bratislavske lekarske listy·2020
Same author

Ampullary cancer in a patient with familial adenomatous polyposis - a rare case report and current status of management.

Bratislavske lekarske listy·2019
Same author

Recurrence after sentinel lymph node biopsy in cutaneous melanoma: a single-center experience in Slovak patients.

Neoplasma·2019
Same journal

Imunological aspects of kidney retransplantation.

Bratislavske lekarske listy·2024
Same journal

The effect of lengthening of the percutaneous implant in the surgical treatment of Th-L ankylosed spine fractures: 4 segment fixation versus 5 to 8 segment fixation.

Bratislavske lekarske listy·2024
Same journal

Prostate cancer in Slovakia: last decade overview.

Bratislavske lekarske listy·2024
Same journal

Cancer epidemiology in Slovakia.

Bratislavske lekarske listy·2024
Same journal

Peculiarities of nutritional support in patients with neoplasms of the hepatopancreatoduodenal zone as a component of intensive therapy in the postoperative period.

Bratislavske lekarske listy·2024
Same journal

A comparative review of coronary computed tomography angiography and myocardial perfusion imaging.

Bratislavske lekarske listy·2024
See all related articles

Systemic antibiotic prophylaxis is crucial for reducing surgical site infections. Optimal timing and duration are key, but prophylaxis cannot replace proper preoperative care and surgical technique.

Area of Science:

  • Infectious Diseases
  • Surgical Site Infections
  • Antibiotic Prophylaxis

Context:

  • Surgical site infections (SSIs) are a significant postoperative complication.
  • Risk factors for SSIs include patient-related, device-related, and environmental factors.
  • Systemic antibiotic prophylaxis is a key strategy to mitigate SSIs.

Purpose:

  • To review the indications, optimal administration, and efficacy of systemic antibiotic prophylaxis in surgical procedures.
  • To highlight the role of antibiotic prophylaxis in high-risk surgeries and its impact on infection rates.

Summary:

  • Systemic antibiotic prophylaxis is indicated for procedures with >5% infection risk, in clean-contaminated wounds, and surgeries with potentially fatal outcomes (e.g., vascular, cardiac, trauma).
  • Second-generation cephalosporins (cefuroxime, cefamandole) are commonly used, with specific regimens for colorectal surgery (e.g., with metronidazole).

Related Experiment Videos

  • Optimal prophylaxis involves administration within 1 hour preoperatively and a duration not exceeding 24 hours, achieving infection rates of 0.5-1.5% in clean procedures.

    • Impact:

    • Antibiotic prophylaxis significantly reduces the incidence of serious infectious complications.
    • While effective, prophylaxis does not substitute for essential preoperative medical management and meticulous surgical technique.
    • Complications associated with antibiotic prophylaxis are infrequent, underscoring its safety profile.