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Recurrent aphthous stomatitis and smoking.

B Tüzün1, R Wolf, Y Tüzün

  • 1Department of Dermatology, Trakya University, Medical Faculty, Edirne, Turkey.

International Journal of Dermatology
|June 10, 2000
PubMed
Summary
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This study found that cigarette smoking is less common in patients with recurrent aphthous stomatitis (RAS). This suggests a protective effect of smoking against developing mouth ulcers, warranting further research into the disease

Area of Science:

  • Dermatology
  • Epidemiology
  • Oral Medicine

Background:

  • Recurrent aphthous stomatitis (RAS) is a common oral condition.
  • Previous studies suggest a potential protective effect of cigarette smoking on RAS.
  • This study aimed to re-evaluate the association between smoking and RAS with dermatologist-confirmed diagnoses.

Purpose of the Study:

  • To investigate the incidence of cigarette smoking in patients diagnosed with recurrent aphthous stomatitis (RAS).
  • To compare smoking habits of RAS patients with control groups.
  • To contribute to understanding the pathogenesis and potential treatments for RAS.

Main Methods:

  • A case-control study design was employed.
  • Thirty-four patients with active RAS lesions, diagnosed by a dermatologist, were compared with 115 outpatients with other skin conditions and 20 healthy controls.

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  • Smoking habits were assessed for all participants.

    • Main Results:

    • A significantly lower percentage of active smokers (8.8%) was observed among patients with RAS compared to control subjects (25.2%).
    • This indicates a negative association between smoking and the occurrence of recurrent aphthous stomatitis.
    • The findings were statistically significant, supporting a protective role of smoking.

    Conclusions:

    • The study confirms a negative epidemiologic association between smoking and recurrent aphthous stomatitis (RAS).
    • This finding supports the hypothesis that smoking may have a protective effect against RAS.
    • Further research can explore the underlying mechanisms and potential therapeutic or preventive strategies for RAS based on this association.