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[Metachronous bilateral Wilms' tumor].

J C Morales Concepción1, E Cordiés Jackson, N Sandin Hernández

  • 1Hospital Pediátrico de Centro Habana, Cuba.

Archivos Espanoles De Urologia
|June 14, 2000
PubMed
Summary

This case report details a female patient diagnosed with metachronous bilateral Wilms' tumor. She achieved long-term survival following surgical intervention and chemotherapy for both kidney tumors.

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Area of Science:

  • Pediatric Oncology
  • Nephrology
  • Cancer Research

Background:

  • Wilms' tumor is the most common pediatric kidney cancer.
  • Metachronous bilateral Wilms' tumor presents a rare clinical challenge.
  • Early detection and comprehensive treatment are crucial for favorable outcomes.

Observation:

  • An 11-year-old female presented with metachronous bilateral Wilms' tumor.
  • Initial diagnosis of right kidney Wilms' tumor at age 4, followed by left kidney tumor detection at age 7.
  • Treatment involved nephrectomy, cobalt therapy, and chemotherapy.

Findings:

  • The patient achieved complete remission after partial nephrectomy and adjuvant chemotherapy for the left kidney tumor.
  • Follow-up imaging revealed normal renal function and growth of remaining renal parenchyma.

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  • The patient remains alive and well over 7 years post-treatment for the second tumor.

    • Implications:

    • This case highlights the possibility of long-term survival in patients with metachronous bilateral Wilms' tumor.
    • It underscores the importance of vigilant surveillance in pediatric cancer survivors.
    • Successful management strategies may involve multimodal therapy including surgery and chemotherapy.