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Updated: Sep 25, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
Published on: March 12, 2016
[The structure of the optic nerve in experimental glaucoma and in the means for its treatment]
V F Ivanova1, E A Mikheeva, V E Karelina
1Laboratory of Medico-Biological Research, I. I. Mechnikov State Medical Academy, St. Petersburg.
Abstract:
Using light and electron microscopy disorders of structure of the optic nerve were studied in rabbits with adrenaline induced glaucoma and after the action of antioxidants (Emoxipine, Erisode) used for preventive and medical purposes. Changes in glaucoma and after administration of drugs in axons and their myelinated sheath were similar but differently pronounced in right and left eye of the same animal. Positive effect of Erisode used for preventive and medical purposes was noted. Emoxipine enhanced the disturbances in optic nerve structure.
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