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Updated: Oct 15, 2026

Three-dimensional Rendering and Analysis of Immunolabeled, Clarified Human Placental Villous Vascular Networks
Published on: March 29, 2018
[The structural manifestations of the adaptive mechanisms occurring in the villous placenta during gestosis]
V D Novikov1, S V Mashak, T V Bachurina
1Department of Histology and Embryology and Cytology, State Medical Academy of Novosibirsk.
Using morphometry, optic and structural analysis and immune histochemistry structural manifestations of adaptive mechanisms in placenta of hemo- and desmochorial type during gestation were studied. Signs of similarity and diversity of realization of adaptive mechanisms at tissue and cellular level were found. Reduction in placental barrier thickness and number of surface capillaries and also activation of trophoblastic elements genome relate to similar signs. Formation of terminal villi is a divergent adaptive mechanism in hemochorial placenta, while intensification of migration of main functionally active cells from trophoblast lining to mother tissue is those in desmochorial placenta.
Using morphometry, optic and structural analysis and immune histochemistry structural manifestations of adaptive mechanisms in placenta of hemo- and desmochorial type during gestation were studied. Signs of similarity and diversity of realization of adaptive mechanisms at tissue and cellular level were found. Reduction in placental barrier thickness and number of surface capillaries and also activation of trophoblastic elements genome relate to similar signs. Formation of terminal villi is a divergent adaptive mechanism in hemochorial placenta, while intensification of migration of main functionally active cells from trophoblast lining to mother tissue is those in desmochorial placenta.
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