[Neuropathies associated with cancers and dysglobulinemias]

Peripheral neuropathies associated to cancers encompass several causes: entrapment or direct involvement of peripheral nerves, paraneoplastic and non tumoral causes, mainly infectious, metabolic or carential. Paraneoplastic neuropathy is mainly the so-called sensory ganglionopathy. A purely motor neuronopathy may be observed in Hodgkin's disease and "terminal" polyneuropathy may complicate may known cancer, in a context of severe weight loss. Polyneuropathies associated with paraproteinaemia include those associated with a defined lymphoproliferative disorder (myelomas, solitary plasmocytoma, Waldenström's disease, lymphoma), and associated with monoclonal gammopathy of undetermined significance.