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New quinolinic derivatives as centrally active antioxidants
G Dorey1, B Lockhart, P Lestage
1Institut de Recherches Servier, Croissy-sur-Seine, France. gdorey@netgrs.com
Bioorganic & Medicinal Chemistry Letters
|June 15, 2000
Abstract:
A series of new 1,2-dihydro and 1,2,3,4-tetrahydroquinolines, synthesized from the corresponding propargylaniline intermediates, have been developed as antioxidants for the potential treatment of pathologies implicating central oxidative stress.