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Exercise training in intermittent claudication.

R Gibellini1, M Fanello, A F Bardile

  • 1Salvatore Maugeri Foundation, IRCCS, Rehabilitation Institute, Montescano, Italy.

International Angiology : a Journal of the International Union of Angiology
|June 15, 2000
PubMed
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Intensive vascular training significantly improves walking distance for patients with peripheral arterial occlusive disease (PAOD). This exercise program offers lasting benefits, with most patients experiencing substantial gains in claudication distances.

Area of Science:

  • Cardiovascular Medicine
  • Exercise Physiology
  • Vascular Surgery

Background:

  • Peripheral arterial occlusive disease (PAOD) significantly impairs walking ability at stage II.
  • Identifying predictors for exercise training outcomes in PAOD is crucial.

Purpose of the Study:

  • To evaluate the efficacy of a 4-week intensive exercise training program followed by a 6-month period in PAOD patients.
  • To analyze risk factors for atherosclerosis and lesion site as potential outcome predictors.

Main Methods:

  • A randomized controlled trial involving 40 PAOD patients (ankle/arm ratio ≤0.7, initial claudication distance (ICD) ≤200m, absolute claudication distance (ACD) ≤500m).
  • Patients were randomized into a supervised walking exercise group (n=20) or a non-exercising control group (n=20).

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  • Assessments were conducted at baseline, 4 weeks (T1), and 6 months (T2), with the training group undergoing a 4-week supervised program.

    • Main Results:

    • The training group showed significant increases in ICD (141% at T1, 200% at T2) and ACD (>1000m in 50% at T1, 70% asymptomatic at T2).
    • 10% of the training group became asymptomatic with >1000m walking distance.
    • The control group exhibited no significant improvement in ICD or ACD.
    • Arterial hypertension and intermittent claudication severity were negative predictors of training outcomes.

    Conclusions:

    • Supervised vascular training leads to significant and enduring improvements in walking distance for PAOD patients.
    • Exercise interventions are effective in managing stage II PAOD symptoms and improving functional capacity.