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Related Concept Videos

Flow Cytometry Analysis of Tissue Factor Expression in Human Platelets10:08

Flow Cytometry Analysis of Tissue Factor Expression in Human Platelets

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This article outlines the protocol for quantifying the percentage of Tissue Factor (TF)-positive platelets using whole blood flow cytometry, assessing the protein: (1) intracellularly in resting conditions, and (2) on the cell surface, in both resting and activated conditions. Guidance is also provided for evaluating TF-positive platelets in platelet-rich...
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We study the effect of surgical masks on cardiopulmonary function based on a cardiopulmonary exercise test (CPET). This study shows that surgical masks reduce cardiopulmonary exercise capacity and ventilation in healthy young subjects and wearing masks might affect aerobic exercise capacity more in female subjects than in male...
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Here, mouse blood was collected in the presence of an anti-coagulant. The platelets were purified by iohexol gradient medium using low speed centrifugation. The platelets were activated with thrombin to investigate if they were viable. The quality of the purified platelets was analyzed by flow cytometry and...
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Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells09:46

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A highly pure population of megakaryocytes can be obtained from cord blood-derived CD34+ cells. A method for CD34+ cell isolation and megakaryocyte differentiation is described...
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Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation09:13

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We describe a straightforward method for the isolation of washed platelets from human blood followed by agonist-induced platelet aggregation measurements by turbidimetry. As an example we apply this method for studying the aggregation response of human platelets to collagen after a pre-incubation with the Pannexin1 channel inhibitor Brilliant Blue...
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The platelet adhesion cascade takes place in the presence of shear flow, a factor not accounted for in conventional (static) well-plate assays. This article reports on a platelet-aggregation assay utilizing a microfluidic well-plate format to emulate physiological shear flow...
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Related Experiment Video

Updated: Jan 26, 2026

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects
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Allergic rhinitis: treating the adult.

J Corren1

  • 1Department of Medicine and Pediatrics, University of California, Los Angeles, CA, USA.

The Journal of Allergy and Clinical Immunology
|June 16, 2000
PubMed
Summary

Allergic rhinitis, a chronic condition, impacts quality of life and healthcare costs. Effective management involves allergen avoidance, medication, and immunotherapy, with new treatments available for difficult cases.

Area of Science:

  • Immunology
  • Allergology
  • Clinical Medicine

Background:

  • Allergic rhinitis is a chronic condition significantly affecting patient quality of life.
  • It represents a considerable burden on healthcare expenditures.
  • Current management strategies are essential for controlling symptoms.

Purpose of the Study:

  • To outline the integrated treatment approach for allergic rhinitis in adults.
  • To highlight the role of pharmacotherapy and immunotherapy.
  • To introduce novel therapeutic options for refractory cases.

Main Methods:

  • Review of current treatment guidelines for allergic rhinitis.
  • Discussion of established treatment modalities including allergen avoidance, pharmacotherapy, and immunotherapy.

More Related Videos

Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation
09:13

Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation

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Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
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Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells

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Related Experiment Videos

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Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation
09:13

Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation

Published on: April 6, 2017

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Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
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Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells

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  • Exploration of emerging treatments like anti-immunoglobulin E therapy and cytokine antagonists.

    • Main Results:

    • An integrated regimen of allergen avoidance, pharmacotherapy, and immunotherapy effectively controls symptoms in most patients.
    • This approach generally results in minimal adverse effects.
    • Newer therapies offer potential relief for patients unresponsive to or intolerant of existing treatments.

    Conclusions:

    • Integrated management is key for effective allergic rhinitis control.
    • Pharmacotherapy and immunotherapy remain cornerstone treatments.
    • Novel medications provide hope for patients with treatment-resistant allergic rhinitis.