Related Experiment Videos
NABC1 (BCAS1): alternative splicing and downregulation in colorectal tumors
R G Correa1, A F de Carvalho, N A Pinheiro
1Ludwig Institute for Cancer Research, São Paulo, Brazil.
Genomics
|June 17, 2000
Abstract:
We have identified a new splicing variant of the gene "novel amplified in breast cancer 1," NABC1 (HGMW-approved symbol BCAS1). This variant, which we call NABC1_5B, uses a previously unidentified 135-bp exon. Also in this report, we confirm that NABC1 is overexpressed in breast tumors and show that both NABC1 and NABC1_5B are downregulated in colorectal tumors.