Acquired tufted angioma of the lower lip mucosa

The acquired tufted angioma is a unique, dusky red, vascular proliferation previously reported in the skin, usually developing in childhood or in young adults, which exhibits a distinctive microscopic appearance. Clinically, the condition enlarges at a variable rate, becomes stable and may regress spontaneously. A small, long-standing, vascular lesion of the mucosa of the lower lip, exhibiting microscopic and immunohistochemical features resembling those of acquired tufted angioma, is reported. The differential diagnosis, including pyogenic granuloma, capillary hemangioma and hemangiopericytoma, is discussed.