[The prostaglandin level in patients with an alcohol dependence syndrome]

A change in the state of the cardiovascular system in patients presenting with gamma alcohol syndrome is mediated by changes in the neurohumoral system and in regulation of the vascular tone and changes in prostaglandins (PG). To study the above-named changes, male subjects aged between 24 to 60 years were examined as were 20 essentially healthy men in the same age bracket. The examined patients demonstrated a marked activation of all kinds of PG during early stages of the presence of gamma alcoholism syndrome. With prolongation of duration of the underlying pathology there comes to be formed a dysbalance with predominance of pressor fractions of PG.