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Updated: Jul 25, 2026

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
Published on: November 28, 2012
Accelerated photostability testing of precision UV(TM) contact lenses
Abstract:
Precision UV(TM) contact lenses were photoaged beyond their expected lifetime in an accelerated manner with a SUNTEST(R) CPS(+) system, which is a solar spectrum equivalent. Ultraviolet spectra of lenses irradiated for 30 h in saline at 41 degrees C and 44 degrees C at the highest power setting were statistically indistinguishable from those measured prior to the exposure. In a similar experiment run at 79 degrees C, the UVB range of the spectra showed small but statistically significant differences, whereas the UVA range of the spectra were not distinguishable. Lenses photoaged at half power and twice the time at 43 degrees C gave UV spectra that could be distinguished. Refractive indices of lenses were indistinguishable before and after irradiation. Eluted materials could not be detected in the saline used to maintain lenses in any irradiation experiment. Lens parameters and water contents remained within manufacturing specifications before and after irradiation.
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