Related Experiment Videos
Immunocytochemical study of giant cell fibroma
1Departamento de Cirurgia Buccal e Patologia, Faculdade de Odontologia, Universidade Federal de Minas Gerais, Belo Horzonte, Brasil.
Brazilian Dental Journal
|June 23, 2000
Abstract:
Giant cell fibroma (GCF) is a non-neoplastic lesion of the oral mucosa. The origin of stellate and multinucleate cells of GCF is not well known. The purpose of the present article was to investigate the immunoreactivity of these cells for leukocyte common antigen, vimentin, tryptase, HLA-DR, alpha-smooth muscle actin, CD68, and S-100. The results showed positive staining only for vimentin. This suggests that the stellate and multinucleate cells of GCF have a fibroblast phenotype.