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Detection of neuroendocrine feature about salivary adenoid cystic carcinoma
1Department of Oral and Maxillofacial Surgery, First Affiliated Hospital, China Medical University (CMU), P. R. China. stfbdc@pub.sy.ln,en
The Chinese Journal of Dental Research
|June 23, 2000
Abstract
Objective:
To study the possibility of neuroendocrine feature of salivary adenoid cystic carcinoma (SACC).
Methods:
Immunohistochemical staining was operated in SACC with S-100 protein, neurospecific enolase (NSE), chromogranin A, and synaptophysin, which are specific and correlative with neuroendocrine cells and neoplasias.
Results:
The positive expression of S-100, NSE, chromogranin, and synaptophysin were 42, 32, 8, and 7, respectively, in 50 cases of SACC.
Conclusion:
Neuroendocrine feature in some SACC cells is possibly indicated.