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Biology versus environment in the extremely low-birth weight infant
B M Lester1, C L Miller-Loncar
1Department of Pediatrics, Brown University School of Medicine, Providence, Rhode Island, USA.
Clinics in Perinatology
|June 23, 2000
Abstract:
This article examines the role of biologic and environmental factors in determining the long-term outcomes of extremely low-birth weight infants. Research focusing on follow-up to at least 4 years of age is reviewed. Methodologic issues related to sampling, the use of control groups, and diagnostic criteria are also discussed. The use of cumulative models of risk for examining the relative contribution of environmental and biologic factors is presented.